. 2024 Jul 17;72(30):16749–16760. doi: 10.1021/acs.jafc.4c03264

Table 3. Omega-6-Derived Oxylipins from M. gaditana, T. lutea, P. tricornutum, and P. cruentum after Ultrasound-Assisted Extraction^a.

		concentration (μg/g)
precursor fatty acid	free oxylipin	M. gaditana	T. lutea	P. tricornutum	P. cruentum
ARA	5-HETE	124.9 ± 60.8^b	1.4 ± 0.8^c	53.2 ± 15.7^bc	228.5 ± 70.1^a
	8-HETE	3.6 ± 2.4^bc	0.9 ± 0.6^c	39.6 ± 12.4^b	142.8 ± 36.7^a
	9-HETE/11-HETE	3.9 ± 2.8^b	0.8 ± 0.5^b	41.9 ± 14.4^b	224.5 ± 61.6^a
	12-HETE	10.8 ± 6.7^b	3.0 ± 1.9^b	147.6 ± 44.2^b	583.5 ± 160.6^a
	15-HETE	4.5 ± 3.1^b	1.3 ± 0.9^b	65.5 ± 16.3^b	255.8 ± 64.2^a
	20-HETE	<LOD	<LOD	62.4 ± 26.3^b	311.8 ± 80.0^a
	5-oxo-ETE	6.0 ± 1.5^b	<LOD	39.3 ± 19.8^b	687.9 ± 240.5^a
	15-oxo-ETE	4.6 ± 3.0^b	<LOD	55.9 ± 21.1^b	367.4 ± 89.6^a
	5,6-EpETrE	0.2 ± 0.1^b	<LOD	0.6 ± 0.2^b	2.0 ± 0.6^a
	8,9-EpETrE/11,12-EpETrE	2.5 ± 1.7^b	<LOD	26.0 ± 9.0^b	141.0 ± 38.7^a
	14,15-EpETrE	2.6 ± 1.7^b	<LOD	40.1 ± 9.2^b	159.9 ± 40.5^a
	5,6-DiHETrE	<LOD	<LOD	1.0 ± 0.2^b	4.4 ± 1.1^a
	11,12-DiHETrE	<LOD	<LOD	<LOD	1.6 ± 0.9
	14,15-DiHETrE	<LOD	2.0 ± 0.9^b	2.2 ± 0.6^b	12.5 ± 2.1^a
	LXA₄	7.1 ± 1.1^b	4.3 ± 2.5^b	199.9 ± 40.0^a	34.7 ± 17.5^b
	PGE₂	2.3 ± 0.7^bc	1.1 ± 0.5^c	11.9 ± 1.1^a	53.0 ± 26.0^ab
LA	12,13-EpOME	0.8 ± 0.5^c	20.4 ± 8.6^b	22.0 ± 6.6^b	38.7 ± 9.1^a
	9,10-EpOME	0.6 ± 0.4^c	14.2 ± 5.6^b	16.9 ± 5.5^ab	26.1 ± 6.3^a
	9,10-DiHOME	<LOD	1.4 ± 0.7^b	<LOD	10.4 ± 6.6^a
	12,13-DiHOME	<LOD	1.8 ± 0.9^b	3.7 ± 1.1^b	8.3 ± 1.7^a
	9-HODE	5.0 ± 2.1^c	111.1 ± 44.2^b	124.8 ± 36.7^ab	186.0 ± 49.2^a
	13-HODE	15.2 ± 6.9^c	336.1 ± 135.5^b	380.7 ± 93.9^b	639.8 ± 160.0^a
	9-oxo-ODE	7.5 ± 3.2^c	69.7 ± 30.1^b	111.2 ± 31.8^ab	152.0 ± 41.1^a
	13-oxo-ODE	<LOD	21.9 ± 10.1^a	13.6 ± 5.0^a	21.7 ± 5.5^a
	9,10,13-TriHOME	5.5 ± 3.1^b	4.0 ± 1.5^b	27.6 ± 9.0^a	2.8 ± 1.1^b
	9,12,13-TriHOME	<LOD	1.0 ± 0.2	<LOD	<LOQ
	Total HpOME	18.3 ± 28.6^b	2.9 ± 1.1^b	<LOD	178.4 ± 85.4^a
	13-HpODE	0.6 ± 0.7^b	0.1 ± 0.0^b	<LOD	5.4 ± 2.8^a
	9-HpOME	<LOD	<LOD	<LOD	0.3 ± 0.2

Data is shown as mean ± SD (n ≥ 3). Different lowercase letters (a, b, c) show statistically significant differences. ARA: arachidonic acid; LA: linoleic acid; HETE: hydroxyeicosatetraenoic acid; Oxo-ETE: oxoeicosatetraenoic acid; EpETrE: epoxyeicosatrienoic acid; DiHETrE: dihydroxyeicosatrienoic acid; LX: lipoxin; PG: prostaglandin; EpOME: epoxyoctadecenoic acid; HOME: hydroxyoctadecenoic acid; HODE: hydroxyoctadecadienoic acid; Oxo-ODE: oxooctadecadienoic acid; HpOME: hydroperoxyoctadecenoic acid; HpODE: hydroperoxyoctadecadienoic acid; LOD: limit of detection; LOQ: limit of quantification.

Table 3. Omega-6-Derived Oxylipins from M. gaditana, T. lutea, P. tricornutum, and P. cruentum after Ultrasound-Assisted Extractiona.

Table 3. Omega-6-Derived Oxylipins from M. gaditana, T. lutea, P. tricornutum, and P. cruentum after Ultrasound-Assisted Extraction^a.