Table 4.
Multivariable Cox Regression Analysis of Factors Associated With AF-Related Hospitalization in Patients With Paroxysmal and Persistent/Permanent Atrial Fibrillation
| 95% CI |
||||
|---|---|---|---|---|
| HR | Low | High | P Value | |
| Paroxysmal AF (84 events) | ||||
| Amiodarone | 1.045 | 0.584 | 1.872 | 0.881 |
| Class Ic antiarrhythmics | 1.861 | 1.116 | 3.101 | 0.017 |
| Digoxin | 1.008 | 0.391 | 2.596 | 0.987 |
| Beta-blockers | 0.804 | 0.506 | 1.277 | 0.355 |
| Verapamil/diltiazem | 0.866 | 0.399 | 1.881 | 0.717 |
| DOAC (vs VKA) | 0.352 | 0.206 | 0.602 | <0.001 |
| Cancer | 1.199 | 0.687 | 2.091 | 0.524 |
| CHA2DS2-VASc score | 0.929 | 0.801 | 1.078 | 0.331 |
| Persistent/permanent AF (96 events) | ||||
| Amiodarone | 3.012 | 1.835 | 4.943 | <0.001 |
| Class Ic antiarrhythmics | 1.947 | 1.069 | 3.548 | 0.029 |
| Digoxin | 1.137 | 0.658 | 1.966 | 0.645 |
| Beta-blockers | 1.521 | 0.989 | 2.340 | 0.056 |
| Verapamil/diltiazem | 2.067 | 1.117 | 3.825 | 0.021 |
| DOAC (vs VKA) | 0.318 | 0.171 | 0.590 | <0.001 |
| Cancer | 1.802 | 1.057 | 3.070 | 0.030 |
| CHA2DS2-VASc score | 0.932 | 0.808 | 1.074 | 0.330 |