Table 1:

Return to school SOPs provided by HCT center directors

Centers	Description
1	Allogeneic: At least 9 months before returning to school
2	Both Allogeneic and Autologous: At least 6–12 months before returning to school Allogeneic: Ok to go back to school after 1 year even on IST
3	Autologous: Minimum 3 months Allogeneic related donor: Minimum 6 months Allogeneic unrelated donor: Minimum 12 months Allogeneic: Check lymphocyte subsets in to verify adequate immunologic function to return
4	Autologous: At least 3 months Allogeneic: At least 6 months and receiving vaccines
5	Both Allogeneic and Autologous: At 1-year post-BMT
6	Allogeneic: off or tapering GVHD meds, CD4+ >200/uL, and receiving vaccines
7	Autologous: ALC >1000/uL, CD4 =200/uL Allogeneic: no GVHD ≥Grade II, ALC >1000/uL, CD4 >400/uL, weaning immunosuppression
8	Allogeneic and Autologous: Response to mitogen & antigen-stimulated lymphocyte proliferation & ready to receive vaccines Allogeneic: No active, uncontrolled GVHD
9	Multiple factors are considered; psychosocial readiness, fatigue, immune suppression, etc.
10	Allogeneic: At least 6 months, receiving vaccines, central catheter removed, and no active GVHD requiring >0.5 mg/kg/day prednisone or ≥2 lines of immunosuppressive therapy
11	Allogeneic: off immune suppression, without active GVHD; with normal ANC and lymphocyte counts; CD4 >400/uL and immunoglobulin levels within normal range for age; receiving vaccines
12	Autologous: after day 50 or at the discretion of primary oncologist and ANC >2000/uL Allogeneic: at least 6–12 months and off systemic immunosuppression

IST= immune suppressive therapy; BMT= bone marrow transplant; GVHD= graft vs. host disease; ALC=absolute lymphocyte count; ANC=absolute neutrophil count