Table 3.

Cardiometabolic risk factors in the definition of MASLD [2]

Metabolic risk factor	Adult criteria
Overweight or Obesity	Body mass index ≥25 kg/m2 (≥23 kg/m2 in people of Asian ethnicity)
	Waist circumference • ≥94 cm in men and ≥80 cm in women (Europeans) • ≥90 cm in men and ≥80 cm in women (South Asians and Chinese) • ≥85 cm in men and ≥90 cm in women (Japanese)
Dysglycaemia or type 2 diabetes	Prediabetes: HbA1c 39-47 mmol/mol (5.7-6.4%) or fasting plasma glucose 5.6-6.9 mmol/L (100-125 mg/dl) or 2-h plasma glucose during OGTT 7.8-11 mmol/L (140-199 mg/dl) orType 2 diabetes: HbA1c ≥48 mmol/mol (≥6.5%) or fasting plasma glucose ≥7.0 mmol/L (≥126 mg/dl) or 2-h plasma glucose during OGTT ≥11.1 mmol/L (≥200 mg/dl) orTreatment for type 2 diabetes
Plasma triglycerides	≥1.7 mmol/L (>150 mg/dl) or lipid-lowering treatment
HDL-cholesterol	≤1.0 mmol/L (<39 mg/dl) in men and ≤1.3 mmol/L (<50 mg/dl) in women or lipid-lowering treatment
Blood pressure	≥130/85 mmHg or treatment for hypertension

HbA1c, glycated haemoglobin; HDL, high-density lipoprotein; OGTT, oral glucose tolerance test.