Table 1.
Description of study cohort.
| Variable | Derivation | Validation | ||
|---|---|---|---|---|
| End-program weight change relative to NIH-BWP | Total | |||
| Less than median | More than median | |||
| N = 894 | N = 867 | N = 1,761 | N = 106 | |
| Mean age, in years (SD) | 46.5 ± 11.7 | 45.8 ± 10.0 | 46.2 ± 10.9 | 48.8 ± 12.6 |
| Female | 728 (81.4%) | 562 (64.8%) | 1,290 (73.3%) | 75 (70.8%) |
| Mean baseline weight, in pounds (SD) | 268.0 ± 53.4 | 276.0 ± 57.6 | 271.9 ± 55.6 | 273.8 ± 55.8 |
| Mean height, inches (SD) | 65.4 ± 3.3 | 66.3 ± 3.8 | 65.9 ± 3.6 | 66.5 ± 3.5 |
| Mean baseline body mass index (SD) | 43.9 ± 7.7 | 43.9 ± 7.1 | 43.9 ± 7.4 | 43.3 ± 7.1 |
| Mean baseline girth, inches (SD) | 48.4 ± 10.9 | 49.3 ± 7.3 | 48.8 ± 9.3 | - |
| Smoking status | ||||
| Never | 458 (51.2%) | 398 (45.9%) | 856 (48.6%) | 67 (63.2%) |
| Previous | 361 (40.4%) | 387 (44.6%) | 748 (42.5%) | 33 (31.3%) |
| Current | 75 (8.4%) | 82 (9.5%) | 157 (8.9%) | 6 (5.7%) |
| Obstructive Sleep Apnea status | ||||
| None | 708 (79.2%) | 629 (72.5%) | 1,337 (75.9%) | 62 (58.5%) |
| OSA, on CPAP | 110 (12.3%) | 144 (16.6%) | 254 (14.4%) | 23 (21.7%) |
| OSA, not on CPAP | 76 (8.5%) | 94 (10.8%) | 170 (9.7%) | 21 (19.8%) |
| Diabetes status | ||||
| None | 593 (66.3%) | 576 (66.4%) | 1,169 (66.4%) | 88 (83.0%) |
| Diet controlled | 156 (17.4%) | 182 (21.0%) | 338 (19.2%) | 4 (3.8%) |
| Weight neutral meds only | 53 (5.9%) | 33 (3.8%) | 86 (4.9%) | 13 (12.3%) |
| Non-Weight neutral meds | 92 (10.3%) | 76 (8.8%) | 168 (9.5%) | 1 (0.9%) |
| Oral glucocorticoids | 10 (1.1%) | 7 (0.8%) | 17 (1.0%) | 1 (0.9%) |
| Antipsychotic | 15 (1.7%) | 12 (1.4%) | 27 (1.5%) | 3 (2.8%) |
| Mean TSH, (SD) | 2.2 ± 1.1 | 2.1 ± 1.0 | 2.2 ± 1.1 | 2.4 ± 1.4 |
| Mean HDL, (SD) | 1.2 ± 0.3 | 1.1 ± 0.3 | 1.2 ± 0.3 | 1.2 ± 0.3 |
| ATPIII metabolic syndrome criteria met | ||||
| Blood pressure | 621 (69.5%) | 639 (73.7%) | 1,260 (71.6%) | 74 (69.8%) |
| Girth | 892 (99.8%) | 865 (99.8%) | 1,757 (99.8%) | 106 (100%) |
| Blood glucose | 352 (39.4%) | 380 (43.8%) | 732 (41.6%) | 52 (49.1%) |
| High density lipoprotein | 553 (61.9%) | 539 (62.2%) | 1,092 (62.0%) | 68 (64.2%) |
| Triglycerides | 352 (39.4%) | 377 (43.5%) | 729 (41.4%) | 47 (44.3%) |
| Number of criteria met | ||||
| 0 | 1 (0.1%) | 1 (0.1%) | 2 (0.1%) | 0 (0%) |
| 1 | 64 (7.2%) | 53 (6.1%) | 117 (6.6%) | 6 (5.7%) |
| 2 | 221 (24.7%) | 176 (20.3%) | 397 (22.5%) | 18 (17.0%) |
| 3 | 275 (30.8%) | 275 (31.7%) | 550 (31.2%) | 39 (36.8%) |
| 4 | 226 (25.3%) | 240 (27.7%) | 466 (26.5%) | 27 (25.5%) |
| 5 | 107 (12.0%) | 122 (14.1%) | 229 (13.0%) | 16 (15.1%) |