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. 2024 Jul 2;49(8):2953–2959. doi: 10.1007/s00261-024-04409-2

Table 2.

Summary of various oral contrasts

Type of oral contrast Indications Not Indicated
Positive oral contrast

- Suspected inter-bowel loop abscesses

- Post-operative bowel leaks*

- Extra-luminal soft tissue density tumors

- Cancer staging and peritoneal carcinomatosis surveillance

- Bowel fistulas*

- Non-acute, nonspecific abdominal pain (in certain contexts)

- Evaluation of small bowel obstruction*

- CT colonography for colorectal cancer screening

- Acute gastrointestinal bleeds

- Diagnosing acute abdominal pain (due to time needed for opacification and visual obstruction)

- Imaging of hepatobiliary, pancreatic, or genitourinary areas

- CT enetrography

- Suspected intraabdominal hemorrhage or gastrointestinal bleeding

- CT angiography- Blunt abdominal trauma (acute)

Neutral oral contrast

- Evaluating inflammatory bowel disease (IBD)

- Intraluminal filling defects including neoplasms

- Causes of recurrent GI bleeds

- Bowel wall calcifications

- CT enetrography (replacing small-bowel follow-through for small-bowel imaging)

- Instances where positive contrast is indicated due to its ability to better delineate certain structures and pathologies
Oral contrast (general) - Certain specific diagnostic and therapeutic applications as mentioned in the indication’s columns for positive and neutral contrasts

- Underlying heart failure

- Allergies to contrast media

- Risk of aspiration

- Situations requiring rapid throughput to avoid delays and increased costs

- Use in patients with specific conditions where the contrast could obscure critical findings or where it provides no direct diagnostic benefit