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. 2024 Jan 18;51(10):3026–3039. doi: 10.1007/s00259-024-06604-1

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Multiple intensity projection (MIP) (top) and transverse fused PET/CT images (bottom) of four vulvar cancer patients. A A 66-year-old woman with left-side unilateral vulvar squamous cell carcinoma (SCC) of 2.5 cm diameter. PET/CT images showing [¹⁸F]-FDG uptake just in the primary tumour (arrowhead). This patient was scheduled for partial vulvectomy and ipsilateral SNB. B A 51-year-old woman with midline vulvar SCC of 3 cm diameter. PET/CT images showing [¹⁸F]-FDG uptake corresponding to the primary tumour (arrowhead) and focal [¹⁸F]-FDG uptake in bilateral inguinal lymph nodes (short arrows). This patient was scheduled for radical vulvectomy and bilateral inguinal lymphadenectomy. C A 65-year-old woman with midline vulvar SCC of 3 cm diameter previously excised. PET/CT images showing focal [¹⁸F]-FDG uptake in bilateral inguinal lymph nodes (short arrows) and bilateral pelvic nodes, which were located in the obturator and external iliac regions (long arrows). This patient was scheduled for upfront chemo-radiotherapy. D An 82-year-old woman with vulvar melanoma. MIP showing focal [¹⁸F]-FDG uptake in the primary vulvar tumour (arrowhead), in the left internal iliac node (long arrow) and bilateral pulmonary nodules (dashed arrows). Transverse fused PET/CT images showing focal [¹⁸F]-FDG uptake corresponding to a sub-centimetric pulmonary nodule localised in the right inferior lobe. This patient was scheduled for systemic therapy