Table 1.
Baseline characteristicsa
| Observation | Radiotherapy | Overall | |
|---|---|---|---|
| (n = 23) n (%) | (n = 27) n (%) | (n = 50) n (%) | |
| Primary site | |||
| Forehead or temple | 2 (8.7) | 4 (14.8) | 6 (12.0) |
| Midface | 4 (17.4) | 7 (25.9) | 11 (22.0) |
| Postauricular | 0 | 1 (3.7) | 1 (2.0) |
| Lip or chin | 4 (17.4) | 6 (22.2) | 10 (20.0) |
| Scalp | 9 (39.1) | 7 (25.9) | 16 (32) |
| Neck | 4 (17.4) | 2 (7.4) | 6 (12) |
| Primary thickness (mm) | |||
| Median (range) | 5.0 (1.1–15.0) | 5.2 (2.0–14.0) | 5.0 (1.1–15.0) |
| Clark level | |||
| III | 1 (4.5) | 0 | 1 (2.1) |
| IV | 7 (31.8) | 5 (20) | 12 (25.5) |
| V | 12 (54.5) | 20 (80) | 32 (68.1) |
| Unknown | 3 (13.0) | 2 (7.4) | 5 (10) |
| Perineural invasion | |||
| Unifocal | 5 (22) | 8 (30) | 13 (26) |
| Multifocal | 9 (39) | 10 (37) | 19 (38) |
| Unknown | 9 (39) | 9 (33) | 18 (36) |
| Largest involved nerve diameter (mm) | |||
| Median (range) | 0.1 (0.05–0.2) | 0.07 (0.04–4) | 0.1 (0.04–4.0) |
| Unknown | 17 (74) | 14 (52) | 31 (62) |
| Ulceration | |||
| Present | 8 (34.8) | 5 (18.5) | 13 (26.0) |
| Microsatellites | |||
| Present | 1 (4.3) | 1 (3.7) | 2 (4.0) |
| Desmoplasia | |||
| Present | 13 (56.5) | 21 (80.8) | 34 (69.4) |
| Mitotic number (per mm2) | |||
| Median (range) | 3.5 (0.0–18.0) | 3.0 (1.0–26.0) | 3.0 (0.0–26.0) |
| Excision margin clearance (mm) | |||
| Lateral: median (range) | 7.0 (0.1–45.0) | 10.0 (0.3–45.7) | 9.5 (0.1–45.7) |
| Deep: median (range) | 3.0 (0.1–13.0) | 1.2 (0.1–11.0) | 2.0 (0.1–13.0) |
| Missing | 5 (23) | 3 (11) | 8 (16) |
aMidface includes cheek, nose, pinna, preauricular