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. 2024 Aug 6;14:18156. doi: 10.1038/s41598-024-69284-9

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Subclusters of macrophages and marker genes of each cluster in mice SkM. (A) The UMAP plot of the six identified clusters. (B) The heatmap, violin plot (C) and the dot plot (D) showing the representative markers across six clusters. (E) The UMAP plot illustrating the macrophages subgroups based on the Lyve1/MHCII expression levels and (F) their marker genes. (G) The relative abundance of macrophages subgroups in young and old mice SkM based on Lyve1/MHCII classification. (H) The UMAP plot representing 11 distinct SkM macrophages subgroups based on marker genes in GSE195507.