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. 2024 Jul 1;49(7):413–420. doi: 10.30476/ijms.2023.98738.3076

Table 3.

Progression of cardiac involvement among patients

Primary echocardiography
Sex Findings Total P value
Normal Mild MR Severe MR Mild MR+mild TR
Female 2 (11.1%) 7 (38.9%) 3 (16.7%) - 12 (66.7%) 0.04
Male 4 (22.3%) 1 (5.5%) - 1 (5.5%) 6 (33.3%)
Six-month follow-up echocardiography
Sex Findings Total P value
Normal Mild MR Moderate to severe MR Severe MR Mild MR+mild TR
Female - 8 (44.5%) - 3 (16.7%) 1 (5.5%) 12 (66.7%) 0.04
Male 3 (16.7%) 2 (11.1%) 1 (5.5%) - - 6 (33.3%)
One-year follow-up echocardiography
Sex Findings Total P value
Normal Mild MR Moderate MR Severe MR Mild MR+mild TR Moderate MR+mild AI
Female - 7 (38.8%) 1 (5.5%) 3 (16.7%) 1 (5.5%) - 12 (66.7%) 0.07
Male 3 (16.7%) 2 (11.1%) - - - 1 (5.5%) 6 (33.3%)

MR: Mitral valve regurgitation; TR: Tricuspid valve regurgitation; AI: Aortic insufficiency; Statistical analysis was performed using Fisher’s exact test. P<0.05 was considered statistically significant.