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. 2024 Jun 17;7(3):364–374. doi: 10.31662/jmaj.2023-0179

Table 5.

Odds Ratios of Underlying Disease for Death by Time Period.

First surge (Jan 29-Jun 13, 2020) Second surge (Jun 14-Oct 9, 2020) Third surge (Oct 10-Dec 24, 2020)
Death / Total participants ORa (95%CI) Death / Total participants ORa (95%CI) Death / Total participants ORa (95%CI)
(n = 86) (n = 1,762) (n = 136) (n = 8,744) (n = 75) (n = 4,358)
Neoplasms
 No 78 / 1,718 1 126 / 8,647 1 70 / 4,280 1
 Yes 8 / 44 1.48 (0.61-3.58) 10 / 97 1.27 (0.61-2.62) 5 / 78 1.04 (0.39-2.76)
Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
 No 82 / 1,747 1 133 / 8,691 1 71 / 4,318 1
 Yes 4 / 15 6.93 (1.48-32.4) 3 / 53 1.58 (0.45-5.60) 4 / 40 3.86 (1.16-12.8)
Endocrine, nutritional, and metabolic diseases
 No 55 / 1,619 1 116 / 8,516 1 69 / 4,199 1
 Yes 31 / 143 3.34 (1.93-5.77) 20 / 228 1.77 (1.03-3.06) 6 / 159 0.86 (0.36-2.10)
Mental and behavioral disorders
 No 86 / 1,756 NA 134 / 8,730 1 75 / 4,356 NA
 Yes 0 / 6 2 / 14 1.78 (0.34-9.22) 0 / 2
Diseases of the nervous system
 No 86 / 1,753 NA 133 / 8,716 1 75 / 4,351 NA
 Yes 0 / 9 3 / 28 1.87 (0.49-7.12) 0 / 7
Diseases of the circulatory system
 No 64 / 1,646 1 122 / 8,525 1 62 / 4,199 1
 Yes 22 / 116 1.58 (0.88-2.84) 14 / 219 0.96 (0.53-1.76) 13 / 159 1.60 (0.83-3.09)
Diseases of the respiratory system
 No 77 / 1,661 1 123 / 8,511 1 65 / 4,154 1
 Yes 9 / 101 1.24 (0.55-2.79) 13 / 233 1.65 (0.87-3.16) 10 / 204 2.38 (1.11-5.06)
Diseases of the digestive system
 No 85 / 1,748 1 134 / 8,699 1 75 / 4,316 NA
 Yes 1 / 14 0.90 (0.10-8.50) 2 / 45 0.70 (0.16-3.16) 0 / 42
Diseases of the skin and subcutaneous tissue
 No 85 / 1,760 NA 136 / 8,743 NA 75 / 4,358 NA
 Yes 1 / 2 0 / 1 0 / 0
Diseases of the musculoskeletal system and connective tissue
 No 84 / 1,748 1 136 / 8,739 NA 74 / 4,356 NA
 Yes 2 / 14 2.62 (0.46-14.8) 0 / 5 1 2
Diseases of the genitourinary system
 No 76 / 1,727 1 133 / 8,675 1 71 / 4,314 1
 Yes 10 / 35 4.82 (1.81-12.8) 3 / 69 0.56 (0.16-1.91) 4 / 44 1.42 (0.46-4.36)

NA, not applicable. a Adjusted by sex and age.