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. 2024 Aug 6;14(34):24585–24603. doi: 10.1039/d4ra04135f

Docking score (kcal mol−1) of synthesized xanthene derivatives (3a–3t) and the reference ligand (4-amino-furo[2,3-d] pyrimidine) against VEGFR-2 enzyme by molecular docking study.

Compound code Docking score
3a −5.08
3b −6.24
3c −6.12
3d −6.02
3e −6.52
3f −4.80
3g −6.01
3h −5.28
3i −6.34
3j −5.80
3k −5.12
3l −6.10
3m −6.20
3n −5.94
3o −5.20
3p −6.80
3q −5.80
3r −6.05
3s −5.40
3t −6.99
Reference ligand −13.11