Table 2.
Number of amino acids, location, and function of different human steroid reductases and their sequence similarities with SRD5A2 and DET2. The online tool, EMBL-EBI (https://www.ebi.ac.uk/Tools/psa/), was used to determine the similarity between different proteins.
| Gene | Function | Amino acids | Chromosome | Similarity % Homosapnian SRD5A2 | Similarity % Plant DET2 |
|---|---|---|---|---|---|
| SRD5A1 | Androgen reduction | 259 | 5p15 | 59 | 48 |
| SRD5A2 | Androgen reduction | 254 | 2p23 | – | 50 |
| SRD5A3 | Polyprenol reduction | 318 | 4q12 | 26 | 32 |
| TECR | trans-2,3-enoyl-CoA reduction | 308 | 19p13 | 26 | 31 |
| TECRL | Unknown | 363 | 4q13 | 25 | 29 |