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. 2024 Jul 1;27(8):110434. doi: 10.1016/j.isci.2024.110434

Table 2.

Information on GO entries enriched by 29 differentially expressed genes

Category ID Item Adjusted p value Gene symbols
Cellular component GO:0098687 chromosomal region 0.033421 CCNB1/BIRC5/PARP1/CHEK2
Cellular component GO:0090575 RNA polymerase II transcription regulator complex 0.009505 NFE2L2/RB1/HIF1A/MYC
Cellular component GO:0045121 membrane raft 0.003898 CASP3/CASP8/CAV1/ICAM1/EGFR
Cellular component GO:0098857 membrane microdomain 0.003898 CASP3/CASP8/CAV1/ICAM1/EGFR
Cellular component GO:0005667 transcription regulator complex 0.000563 CCND1/PARP1/NFE2L2/RB1/HIF1A/MYC/RELA
Molecular function GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process 5.43E-05 CASP3/CASP9/CASP8
Molecular function GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway 1.96E-05 CASP3/CASP9/CASP8
Molecular function GO:0140297 DNA-binding transcription factor binding 1.96E-05 PARP1/NFE2L2/BCL2/RB1/HIF1A/NFKBIA/MYC/RELA
Molecular function GO:0031625 ubiquitin protein ligase binding 4.38E-08 ERBB3/CASP8/BCL2/RB1/HIF1A/EGFR/CHEK2/NFKBIA/RELA
Molecular function GO:0044389 ubiquitin-like protein ligase binding 5.13E-09 CCNB1/ERBB3/CASP8/BCL2/RB1/HIF1A/EGFR/CHEK2/NFKBIA/RELA
Biological process GO:0010038 response to metal ion 1.03E-09 CASP3/CASP9/CCND1/PARP1/NFE2L2/CASP8/BCL2/CAV1/HIF1A/VCAM1/EGFR
Biological process GO:0071466 cellular response to xenobiotic stimulus 1.03E-09 GSTP1/NFE2L2/CYP3A4/RB1/POR/GSTM1/CHEK2/CYP1B1/MYC
Biological process GO:0009314 response to radiation 7.88E-10 CASP3/CASP9/CCND1/PARP1/BCL2/HIF1A/VCAM1/EGFR/CHEK2/MYC/COL3A1/RELA
Biological process GO:0062197 cellular response to chemical stress 7.88E-10 CASP3/PARP1/NFE2L2/BCL2/CAV1/HIF1A/AKR1B1/EGFR/CYP1B1/MYC/RELA
Biological process GO:0009410 response to xenobiotic stimulus 7.74E-10 CASP3/CCND1/GSTP1/NFE2L2/BCL2/CYP3A4/RB1/POR/GSTM1/CHEK2/CYP1B1/MYC