Table 3.

Fold changes in plasma bile acids measured by liquid chromatography–tandem mass spectrometry analyzed by the matched pairs t-test.

Bile acid	Low-dose glucagon infusion			High-dose glucagon infusion
	Fold change	P-value	q-value	Fold change	P-value	q-value
Cholate	0.13	0.0623	0.0475	0.24a	0.0488	0.0566
Taurocholate	0.37	0.1416	0.0807	0.24a	0.0027	0.0122
Taurochenodeoxycholate	0.48	0.131	0.0766	0.15a	0.0019	0.0104
β-Muricholate	0.11a	0.0066	0.0133	0.22a	0.0013	0.0101
α-Muricholate	0.14a	0.0046	0.0111	0.22a	0.0005	0.0091
Tauro-β-muricholate	0.26	0.074	0.0521	0.16a	0.0044	0.0154
Deoxycholate	0.23	0.0702	0.0509	0.38	0.0844	0.0815
Taurodeoxycholate	0.39	0.1357	0.0786	0.10a	0.0009	0.0096
Lithocholate	1	–	–	1	–	–
Taurolithocholate	0.25	0.0509	0.0415	0.07a	0.0004	0.0086
Ursodeoxycholate	0.14a	0.0063	0.0131	0.18a	0.0021	0.0109
Tauroursodeoxycholate	0.32	0.0707	0.051	0.19a	0.0074	0.0182
Taurohyodeoxycholic acid	0.29a	0.0013	0.0074	0.27a	0.0099	0.0217
12-Dehydrocholate	0.13a	0.0386	0.0352	0.25a	0.0099	0.0217
7-Ketodeoxycholate	0.11a	0.0188	0.0224	0.24a	0.0059	0.0166
Ursocholate	0.26	0.0664	0.0499	0.49a	0.0204	0.0316

^a P < 0.05.