Table 5.

Analysis of the efficacy of IMA and BDNF and their combination for diagnosing CCH

Serum marker	Cut-off value	AUC	95% CI		p-value	Specificity	Sensitivity	Youden’s index
			Lower limit	Upper limit
IMA+BDNF	-	0.803	0.708	0.898	< 0.001	0.655	0.855	0.510
IMA	24.292	0.738	0.627	0.848	< 0.001	0.621	0.836	0.457
BDNF	6.714	0.631	0.512	0.751	0.049	0.931	0.418	0.349

CCH: chronic cerebral hypoperfusion; BDNF: brain-derived neurotrophic factor; IMA: ischemia-modified albumin.