. 2024 Jul 13;13(4):e240089. doi: 10.1530/ETJ-24-0089
This work is licensed under a Table 1.
Diagnostic efficiency of [18F]F-DOPA PET.
| TP | TN | Sensitivity | Specificity | Accuracy | PPV | NPV | |
|---|---|---|---|---|---|---|---|
| Patient-related diagnostic efficiency | |||||||
| Total | 81 | 28 | 95% (77/81) | 93% (26/28) | 94% (103/109) | 97% (77/79) | 87% (26/30) |
| F | 41 | 9 | 98% (40/41) | 89% (8/9) | 96% (48/50) | 98% (40/41) | 89% (8/9) |
| M | 40 | 19 | 93% (37/40) | 95% (18/19) | 93% (55/59) | 97% (37/38) | 86% (18/21) |
| P ( F vs M) | 0.590 | 0.548 | 0.832 | 1.000 | 1.000 | ||
| PMTC | 50 | 0 | 92% (46/50) | 92% (46/50) | 100% (46/46) | ||
| RMTC | 31 | 28 | 100% (31/31) | 93% (26/28) | 97% (57/59) | 94% (31/33) | 100% (26/26) |
| P (PMTC vs RMTC) | 0.277 | – | 0.529 | 0.171 | – | ||
| HMTC | 7 | 5 | 100% (7/7) | 100% (5/5) | 100% (12/12) | 100% (7/7) | 100% (5/5) |
| SMTC | 74 | 23 | 95% (70/74) | 91% (21/23) | 94% (91/97) | 97% (70/72) | 84% (21/25) |
| P (HMTC vs SMTC) | 1.000 | 1 000 | 1 000 | 1.000 | 1.000 | ||
| Lesion-related diagnostic efficiency | |||||||
| Total | 775 | 205 | 65 % (501/775) | 99% (203/205) | 72% (704/980) | 99% (501/503) | 43% (203/477) |
| F | 300 | 93 | 60% (181/300) | 99% (92/93) | 69% (273/393) | 99% (181/182) | 44% (92/211) |
| M | 475 | 112 | 68% (321/475) | 99% (111/112) | 73% (431/587) | 99% (320/321) | 42% (111/266) |
| P ( F vs M) | 0.040 | 1.000 | 0.177 | 1.000 | 0.681 | ||
| PMTC | 563 | 0 | 51% (289/563) | 51% (289/563) | 100% (289/289) | ||
| RMTC | 212 | 205 | 100% (212/212) | 99% (203/205) | 99% (415/417) | 99% (212/214) | 100% (203/203) |
| P (PMTC vs RMTC) | 0.000 | 0.000 | 0.181 | ||||
| HMTC | 51 | 26 | 25% (13/51) | 100% (26/26) | 51% (39/77) | 100% (13/13) | 41% (26/64) |
| SMTC | 724 | 179 | 67% (488/724) | 99% (177/179) | 74% (665/903) | 99% (488/490) | 43% (177/413) |
| P (HMTC vs SMTC) | 0.000 | 1.000 | 0.000 | 1.000 | 0.737 | ||
| LN | 510 | 58 | 54% (276/510) | 98% (57/58) | 59% (333/568) | 99% (276/277) | 20% (57/291) |
| DM | 185 | 91 | 88% (162/185) | 100% (91/91) | 92% (253/276) | 100% (162/162) | 80% (91/114) |
DM, distant metastases; F, female; HMTC, hereditary MTC; LK, lymph node lesions; M, male; NPV, negative predictive value; PMTC, primary MTC; PPV, positive predictive value; RMTC, recurrent MTC; SMTC, sporadic MTC; TN, true negative; TP, true positive.