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Range of placements of the search sphere when searching for the megabody component. The GABA receptor structure is shown in blue and the megabody is in magenta. (a) Sphere center placed 9 Å closer to the fivefold symmetry axis than the center of the correctly placed megabody component, substantially overlapping the GABA receptor component. (b) Sphere center placed 9 Å farther from the axis, minimally overlapping the GABA receptor component.
