Table 1.
Baseline characteristics of the study population, overall and by hrHPV positivity in cervical cancer cases from Muhimbili National Hospital in Tanzania
| Characteristic/Categories | All: N = 227 n (col%) |
hrHPV Negative n (row%) |
hrHPV Positive n (row%) |
P value* |
|---|---|---|---|---|
| All | ||||
| Age groups (years) | ||||
| 30–40 | 31 (13.7) | 11 (35.5) | 29 (64.5) | 0.04 |
| 41–60 | 121 (53.3) | 18 (14.9) | 103 (85.1) | |
| ≥ 61 | 75 (33.0) | 14 (18.7) | 61 (81.3) | |
| Parity | ||||
| 0–5 | 72 (31.7) | 15 (20.8) | 57 (79.2) | 0.75 |
| ≥ 6 | 91 (40.1) | 15 (16.5) | 76 (83.5) | |
| Missing | 64 (28.2) | 13 (20.3) | 51 (79.7) | |
| HIV status | ||||
| Negative | 45 (19.8) | 12 (26.7) | 33 (73.3) | 0.24 |
| Positive | 65 (28.6) | 13 (20.0) | 52 (80.0) | |
| Unknown | 117 (51.5) | 18 (15.4) | 99 (84.6) | |
| Histologic subtype | ||||
| SCC | 207 (91.2) | 33 (15.9) | 174 (84.1) | 0.001 |
| ADC† | 20 (8.8) | 10 (50.0) | 10 (50.0) | |
Abbreviations hrHPV, high-risk human papillomavirus; HIV, human immunodeficiency virus; SCC, squamous cell carcinoma; ADC, adenocarcinoma
*Fisher’s exact test comparing hrHPV negative vs. positive
†Includes 4 cases of adenosquamous carcinoma