Table 2.
Distribution of high-risk HPV types by HIV status in cervical cancer cases from Muhimbili National Hospital in Tanzania
| hrHPV type detected | All {n = 227, 100%} n (col%) |
HIV negative {n = 45; 19.8%} n (col%) |
HIV positive {n = 65, 28.6%} n (col%) |
HIV unknown {n = 117, 51.6%} n (col%) |
P value* |
|---|---|---|---|---|---|
| Any hrHPV | 184 (81.1) | 33 (73.3) | 52 (80.0) | 99 (84.6) | 0.49 |
| HPV16 | 100 (44.1) | 14 (31.1) | 28 (43.1) | 58 (49.6) | 0.24 |
| HPV18 | 36 (15.9) | 8 (17.8) | 11 (16.9) | 17 (14.5) | 1.00 |
| HPV31 | 0 | 0 | 0 | 0 | n/a |
| HPV33 | 5 (2.2) | 2 (4.4) | 1 (1.5) | 2 (1.7) | 0.57 |
| HPV35 | 19 (8.4) | 2 (4.4) | 6 (9.2) | 11 (9.4) | 0.47 |
| HPV39 | 3 (1.3) | 2 (4.4) | 0 (0) | 1 (0.9) | 0.17 |
| HPV45 | 13 (5.7) | 4 (8.9) | 1 (1.5) | 8 (6.8) | 0.16 |
| HPV51 | 1 (0.4) | 0 (0) | 0 (0) | 1 (0.9) | n/a |
| HPV52 | 4 (1.8) | 1 (2.2) | 2 (3.1) | 1 (0.9) | 1.00 |
| HPV56 | 1 (0.4) | 0 (0) | 0 (0) | 1 (0.9) | n/a |
| HPV58 | 10 (4.4) | 3 (6.7) | 6 (9.2) | 1 (0.9) | 0.74 |
| HPV59 | 2 (0.9) | 0(0) | 1 (1.5) | 1 (0.9) | 1.00 |
| HPV66 | 3 (1.3) | 0(0) | 1 (1.5) | 2 (1.7) | 1.00 |
| HPV68 | 10 (4.4) | 0(0) | 7 (10.8) | 3 (2.6) | 0.04 |
| Number of hrHPV types detected | |||||
| 1 | 162 (88.0) | 30 (90.9) | 40 (76.9) | 92 (92.9) | 0.15 |
| 2 or more | 22 (12.0) | 3 (9.1) | 12 (23.1) | 7 (7.1) | |
Abbreviations hrHPV, high-risk human papillomavirus; HIV, human immunodeficiency virus; n/a, not available
*Fisher’s exact test comparing HIV negative vs. positive