Adam 1978.

Study characteristics
Methods	Trial design: randomised, parallel study Trial registration number: not reported Country: Malaya Outpatient or hospital, date trial conducted, duration of trial participation: not reported Inclusion criteria: patients with skin disease because of contact eczema, photosensitivity, discoid eczema, AD or psoriasis Exclusion criteria: not reported Additional design details: AD participants were a subset with some results reported separately.
Participants	Total number randomised: 14 participants with AD (8 to apply the intervention and 6 to apply the comparator) Age, sex, ethnicity, duration of eczema, severity of eczema, body site, number of withdrawals: not reported Notes: none
Interventions	Run‐in details: no topical applications for at least two weeks prior to trial Intervention: desoximetasone 0.25% ointment used twice daily for ≥ 30 days · Concurrent treatment: not reported · Other key information: Brand: Esperson Comparator: betamethasone valerate (assumed 0.05%) ointment used twice daily for ≥ 30 days · Concurrent treatment: not reported · Other key information: none Concurrent treatments received alongside both intervention and comparator: to quote: "No other treatment was given". Notes: none
Outcomes	Response to therapy at up to one month was grouped as: excellent to good, fair and poor. In "Excellent to good" response, the skin condition cleared and remission was maintained throughout their follow‐up. In "Fair" response, both symptoms and signs were less but there was no remission. If skin change remained as it was in the first visit or improvement was minimal, the response was categorised as "Poor".
Notes	Funding source: Hoechst Malaysia Sdn. Bhd Declarations of interest: not declared Original language of publication: English Other: none