Dou 2006b.

Study characteristics
Methods	Trial design: randomised, double‐blind, multicentre, parallel study Trial registration number: not reported Country: China Outpatient or hospital: two departments of Dermatology Date trial conducted: July 2003 to January 2004 Duration of trial participation: not reported Inclusion criteria: patients with AD Exclusion criteria: not reported Additional design details: the paper reported two separate trials; Dou 2006a = adults, Dou 2006b = children
Participants	Total number randomised: 104 participants (51 to apply the intervention and 53 to apply the comparator) Age: 5 to 17 years n = 104, intervention n = 51, comparator n = 53; 2 to 4 years n = 21, intervention n = 12; comparator n = 9 Sex, ethnicity, duration of eczema, severity of eczema, body site, number of withdrawals: not reported Notes: none
Interventions	Run‐in details: not reported Intervention: tacrolimus 0.03% ointment used twice daily for 21 days · Concurrent treatment: not reported · Other key information: none Comparator: vehicle ointment used twice daily for 21 days · Concurrent treatment: not reported · Other key information: none Concurrent treatments received alongside both intervention and comparator: not reported Notes: none
Outcomes	Quality of life using the CDLQI scale
Notes	Funding source: Fujisawa Pharmaceutical (China) Co., Ltd. provided assistance for this study; Shanghai Nisshin, Pharmaceutical Development Co., Ltd. manages and counts the data of this observation. Declarations of interest: not declared Original language of publication: Chinese Other: none