Skip to main content
. 2024 Aug 6;2024(8):CD015064. doi: 10.1002/14651858.CD015064.pub2

Hung 2007.

Study characteristics
Methods Trial design: randomised, single‐centre, parallel study
Trial registration number: not reported
Country: Taiwan
Outpatient or hospital: outpatients
Date trial conducted: February 2004 to February 2005
Duration of trial participation: 8 weeks
Inclusion criteria: AD according to Hanifin and Rajka criteria; moderate‐to‐severe according to Rajka and Langeland criteria
Exclusion criteria:
· Systemic topical antibiotics or corticosteroids within 4 weeks of the study
· Clinical signs of secondary infection
Additional design details: not reported
Participants Total number randomised: 60 participants (30 to apply the intervention and 30 to apply the comparator)
Age: mean 15.6 years, range from 9 months to 33 years
Sex: male n = 26, female n = 34
Ethnicity, duration of eczema: not reported
Severity of eczema: SCORAD mean 55.3 (standard error of mean (SEM) 1.9)
Body site, number of withdrawals: not reported
Notes: not reported
Interventions Run‐in details: not reported
Intervention: fluticasone propionate 0.05% cream used twice daily for 8 weeks
· Concurrent treatment: not reported
· Other key information: none
Comparator: tacrolimus 0.03% ointment used twice daily for 8 weeks
· Concurrent treatment: not reported
· Other key information: none
Concurrent treatments received alongside both intervention and comparator. Participants were instructed to apply the treatment regimen to all affected areas, without occlusion. In those who used fusidic acid cream, it was applied first to all affected areas followed by fluticasone propionate or tacrolimus 20 minutes later.
Notes: none
Outcomes · SCORAD
· BSA
Notes Funding source: not reported
Declarations of interest: not declared
Original language of publication: English
Other: none