Hung 2007.
| Study characteristics | |
| Methods | Trial design: randomised, single‐centre, parallel study Trial registration number: not reported Country: Taiwan Outpatient or hospital: outpatients Date trial conducted: February 2004 to February 2005 Duration of trial participation: 8 weeks Inclusion criteria: AD according to Hanifin and Rajka criteria; moderate‐to‐severe according to Rajka and Langeland criteria Exclusion criteria: · Systemic topical antibiotics or corticosteroids within 4 weeks of the study · Clinical signs of secondary infection Additional design details: not reported |
| Participants | Total number randomised: 60 participants (30 to apply the intervention and 30 to apply the comparator) Age: mean 15.6 years, range from 9 months to 33 years Sex: male n = 26, female n = 34 Ethnicity, duration of eczema: not reported Severity of eczema: SCORAD mean 55.3 (standard error of mean (SEM) 1.9) Body site, number of withdrawals: not reported Notes: not reported |
| Interventions | Run‐in details: not reported Intervention: fluticasone propionate 0.05% cream used twice daily for 8 weeks · Concurrent treatment: not reported · Other key information: none Comparator: tacrolimus 0.03% ointment used twice daily for 8 weeks · Concurrent treatment: not reported · Other key information: none Concurrent treatments received alongside both intervention and comparator. Participants were instructed to apply the treatment regimen to all affected areas, without occlusion. In those who used fusidic acid cream, it was applied first to all affected areas followed by fluticasone propionate or tacrolimus 20 minutes later. Notes: none |
| Outcomes | · SCORAD · BSA |
| Notes | Funding source: not reported Declarations of interest: not declared Original language of publication: English Other: none |