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. 2024 Aug 6;2024(8):CD015064. doi: 10.1002/14651858.CD015064.pub2

Levy 1974.

Study characteristics
Methods Trial design: randomised, double‐blind, within‐participant study
Trial registration number: not reported
Country: USA
Outpatient or hospital: outpatient
Date trial conducted: not reported
Duration of trial participation: 21 days
Inclusion criteria: comparable, symmetrical areas of steroid‐responsive dermatoses
Exclusion criteria: not reported
Additional design details: this study also included 25 patients with psoriasis and with miscellaneous corticosteroid responsive dermatoses.
Participants Total number randomised: 44 sides treated (22 to apply the intervention and 22 to apply the comparator)
Age: 10 to 67 years
Sex: male n = 12, female n = 10
Ethnicity: not reported
Duration of eczema: 4 months to 60 years
Severity of eczema, body site: not reported
Number of withdrawals: 7 patients withdrew but this was not separated by skin condition.
Notes: none
Interventions Run‐in details: not reported
Intervention: fluocinonide 0.05% FAPG used twice daily for 21 days
· Concurrent treatment: not reported
· Other key information: none
Comparator: vehicle FAPG used twice daily for 21 days
· Concurrent treatment: not reported
· Other key information: none
Concurrent treatments received alongside both intervention and comparator: not reported
Notes: FAPG is a specially designed base that combines the physical properties of a cream and a gel.
Outcomes · Improvement evaluation based mainly on the appearance of the lesions in the test areas. The categories of scoring were: very good or excellent; moderate improvement; and no improvement or worse.
Notes Funding source: not reported
Declarations of interest: not declared
Original language of publication: English
Other: none