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. 2024 Aug 6;2024(8):CD015064. doi: 10.1002/14651858.CD015064.pub2

Ludvigsen 1975.

Study characteristics
Methods Trial design: randomised, double‐blind, within‐participant study
Trial registration number: not reported
Country: Denmark
Outpatient or hospital, date trial conducted: not reported
Duration of trial participation: 14 days
Inclusion criteria: AD with similar lesions
Exclusion criteria: not reported
Additional design details: none
Participants Total number randomised: 50 participants (50 sides to apply the intervention and 50 sides to apply the comparator)
Age: range from 6 months to 22 years
Sex, ethnicity, duration of eczema, severity of eczema, body site: not reported
Number of withdrawals: 4 did not attend follow‐up; reason why not provided
Notes: none
Interventions Run‐in details: not reported
Intervention: calmuril‐hydrocortisone 1% cream used twice daily for "approx" 14 days
· Concurrent treatment: not reported
· Other key information: none
Comparator: triamcinolone acetonide 0.1% cream used twice daily for "approx" 14 days
· Concurrent treatment: not reported
· Other key information: none
Concurrent treatments received alongside both intervention and comparator: not reported
Notes: none
Outcomes · to quote: "morphological exemplification changes"
· Itch
· Dryness
· Patient preference
· AE
Notes Funding source: not reported
Declarations of interest: not declared
Original language of publication: Danish
Other: Paper in Danish. Translation via google translation and google app, plus advice of native Danish speaker on results