Rahman 2015.

Study characteristics
Methods	Trial design: randomised study Trial registration number: not reported Country: Bangladesh Outpatient or hospital: Department of Dermatology and Venereology Date trial conducted: March 2012 to 2013 Duration of trial participation: 6 weeks Inclusion criteria: · Aged 2 to 10 years · Intermittent or persistent symptoms of AD according to Hanifin‐Rajka criteria · AD for at least one year Exclusion criteria: not reported Additional design details: none
Participants	Total number randomised: 60 participants (30 to apply the intervention and 30 to apply the comparator) Age: 2 to 10 years. Mean age tacrolimus group, 5.97 years (SD 2.25); hydrocortisone group, 5.4 years (SD 2.66) Sex: 53.3% male, 46.7% female Ethnicity: not reported Duration of eczema: at least a year Severity of eczema, body site: not reported Number of withdrawals: there were no withdrawals. Notes: none
Interventions	Run‐in details: washout phase of 2 weeks Intervention: tacrolimus 0.03% ointment used twice daily for 21 days · Concurrent treatment: not reported · Other key information: none Comparator: hydrocortisone acetate 1% ointment used twice daily for 21 days · Concurrent treatment: not reported · Other key information: none Concurrent treatments received alongside both intervention and comparator: no concurrent treatments were allowed during the study. Notes: none
Outcomes	· EASI · AE · Evaluation of erythema, oedema/induration/papulation, excoriation, oozing/weeping/crusting, scale and lichenification
Notes	Funding source: not reported Declarations of interest: not declared Original language of publication: not reported Other: none