Gutgesell 1998.

Methods	Trial design: double‐blind, within‐participant study Trial registration number, country, outpatient or hospital, date trial conducted, duration of trial participation: not reported Inclusion criteria: adults with severe longstanding AD Exclusion criteria: not reported Additional design details: study awaiting classification as unclear if randomised
Participants	Total number randomised: number reported but not clear if randomised Age: 22 to 36 years Sex, ethnicity, duration of eczema, severity of eczema, body site, number of withdrawals: not reported Notes: none
Interventions	Run‐in details: not reported Intervention: tacrolimus 0.1% ointment used once or twice daily for 21 days · Concurrent treatment: not reported · Other key information: none Comparator: hydrocortisone 3.% ointment used once or twice daily for 21 days · Concurrent treatment: not reported · Other key information: none Concurrent treatments received alongside both intervention and comparator: the area of treatment did not exceed 20% of the whole BSA. Notes: none
Outcomes	· Modified SCORAD · Pruritus · AE
Notes	Funding source: not reported Declarations of interest: not declared Original language of publication: English Other: unclear study design (abstract only)