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. 2024 Aug 6;2024(8):CD015064. doi: 10.1002/14651858.CD015064.pub2

Rhemus 2006.

Study name A double‐blind, placebo‐controlled study of a natural topical anti‐inflammatory for treatment of atopic dermatitis and psoriasis
Methods Trial design: randomised, double‐blind study
Trial registration number: not reported
Country: US
Outpatient or hospital, date trial conducted: not reported
Duration of trial participation: 8 weeks
Inclusion criteria:
· Mild‐to‐moderate AD
· Contralateral plaques
Exclusion criteria: not reported
Additional design details: to quote: "Subjects were randomized into 1 of 4 groups. Each group received the active cream, which was applied to one plaque and either hydrocortisone 1% or placebo to apply to the contralateral plaque".
Participants Total number randomised, age, sex, ethnicity, duration of eczema, severity of eczema, body site: not reported
Number of withdrawals: no results
Notes: none
Interventions Run‐in details: not reported
Intervention: hydrocortisone 1.% cream
· Concurrent treatment: not reported
· Other key information: in the trial, TCS is one of two comparators; the other is a placebo.
Comparator: vehicle/placebo
· Concurrent treatment: not reported
· Other key information: none
Concurrent treatments received alongside both intervention and comparator: not reported
Notes: none
Outcomes To quote: "Standard quantitative and qualitative assessments of atopic dermatitis were performed at baseline visit, week 2, and week 4".
Starting date Not reported
Contact information Not reported
Notes Funding source: Nu Skin Enterprises
Declarations of interest: not declared
Original language of publication: English
Other: none