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. 2024 Jun 27;12(8):e00199-24. doi: 10.1128/spectrum.00199-24

TABLE 2.

Inhibition zone sizes (mm) by naturally occurring compounds against RGM strains in the disk diffusion assaysa

Strains tCIN CAR CIT GER GEN PHL AMI
M. abscessus
 MAB1 43 14 40 28 19 16 24
 MAB4 33 16 40 40 17 15 23
 MAB5 35 16 L 36 18 15 25
M. chelonae
 MC4 55 12 L 32 32 29 40
 MC6 L L 41 L 21 32 29
 MC7 L 14 L L 22 22 16
M. fortuitum
 MF1 30 14 22 20 17 19 16
 MF3 54 13 27 21 21 22 20
 MF6 15 13 30 26 17 21 21
M. smegmatis
 ATCC 14468 42 44 44 26 16 18 30
a

tCIN, trans-cinnamaldehyde (99 mg/mL); CAR, carvacrol (39.2 mg/mL); CIT, citral (95 mg/mL); GER, geraniol (98 mg/mL); GEN, gentisaldehyde (50 mg/mL); PHL, phloroglucinaldehyde (50 mg/mL); AMI, amikacin (3 mg/mL). Liquid compounds were tested for their highest concentrations and solid compounds were tested for the stock solutions. “L” indicates the inhibition zone size larger than 60 mm. “-” indicates no inhibition. Paper disk diameter 8 mm; test volume 20 μL. M. smegmatis ATCC 14468 was a non-pathogenic RGM reference strain to test for comparison.