Table 1. Comparison of General Information on Critically Ill Pediatrics Between the Two Groups of Intervention a.
| Variables | All Patients (n = 68, 100%) | CIV (n = 33, 48.53%) | IIV (n = 35, 51.47%) | P-Value |
|---|---|---|---|---|
| General information | ||||
| Age (mo) | 38.96 ± 43.85 | 35.50 ± 41.75 | 42.22 ± 46.10 | 0.305 |
| Age (y) | 0.490 | |||
| Younger than one year | 26 (38.24) | 14 (42.42) | 12 (34.29) | |
| Older than one year | 42 (61.76) | 19 (57.58) | 23 (65.71) | |
| Gender | 0.038 b | |||
| Female | 25 (36.76) | 8 (24.24) | 17 (48.57) | |
| Male | 43 (63.24) | 25 (75.76) | 18 (51.43) | |
| Underlying diseases | 0.190 | |||
| CNS disease | 11 (16.18) | 6 (18.18) | 5 (14.29) | |
| Endocrine and metabolic syndrome | 5 (7.35) | 2 (6.06) | 3 (8.57) | |
| Gastrointestinal diseases | 15 (22.06) | 10 (30.30) | 5 (14.29) | |
| Blood disorders | 5 (7.35) | 0 (0.00) | 5 (14.29) | |
| Others | 11 (16.18) | 6 (18.18) | 5 (14.29) | |
| None | 21 (30.88) | 9 (27.27) | 12 (34.29) | |
| Chief complaint (yes) | 0.079 | |||
| Seizure | 9 (13.24) | 7 (21.21) | 2 (5.71) | |
| Loss of consciousness | 4 (5.88) | 4 (12.12) | 0 (0.00) | 0.050 |
| Post-operation | 22 (32.35) | 12 (36.36) | 10 (28.57) | 0.492 |
| Respiratory distress | 34 (50.00) | 11 (33.33) | 23 (65.71) | 0.008 b |
| Others c | 10 (14.71) | 5 (15.15) | 5 (14.59) | 0.920 |
| Hospitalization and follow-up during treatment | ||||
| Vital status | ||||
| Alive discharged | 47 (70.15) | 20 (60.61) | 27 (79.41) | 0.093 |
| Died | 20 (29.85) | 13 (39.39) | 7 (20.59) | |
| Mechanical ventilation (yes) | 44 (64.71) | 25 (75.76) | 19 (54.29) | 0.064 |
| Ventilation time (day) | 10.25 ± 8.46 | 10.26 ± 8.29 | 10.23 ± 8.87 | 0.755 |
| Length of ICU stay (day) | 22.30 ± 24.94 | 22.54 ± 14.10 | 22.17 ± 32.23 | 0.168 |
| Length of hospital stay (day) | 30.14 ± 30.76 | 27.63 ± 15.12 | 32.51 ± 40.46 | 0.457 |
| Clinical characteristics | ||||
| Height (cm) | 88.54 ± 26.18 | 86.21 ± 24.30 | 90.74 ± 28.01 | 0.407 |
| Weigh (kg) | 13.19 ± 10.50 | 13.12 ± 11.77 | 13.25 ± 9.32 | 0.491 |
| Pediatric Risk of Mortality (PRISM) score | 6.91 ± 4.24 | 7.72 ± 4.09 | 6.14 ± 4.29 | 0.097 |
Abbreviations: CIV, continuous infusions of vancomycin; IIV, intermittent infusions of vancomycin; CNS, central nervous system; PRISM, pediatric risk of mortality.
a Values are expressed as No. (%) or mean ± SD.
b Statistically significant at P-value < 0.05.
c Such as respiratory, cardiovascular, musculoskeletal, or neuromuscular disorders.