Table 3.
MR result of casual effects between gut microbiome and the risk of delirium.
| Group | Bacterial | Nsnp | Methods | SE | OR (95% CI) | P-value |
|---|---|---|---|---|---|---|
| Phylum | Verrucomicrobia | 12 | Inverse variance weighted | 0.183 | 1.444 (1.009, 2.065) | 0.044 |
| MR Egger | 0.478 | 1.740 (0.682, 4.438) | 0.273 | |||
| Simple mode | 0.411 | 2.053 (0.917, 4.596) | 0.108 | |||
| Weighted median | 0.259 | 1.505 (0.906, 2.500) | 0.114 | |||
| Weighted mode | 0.347 | 1.473 (0.746, 2.906) | 0.288 | |||
| Family | Desulfovibrionaceae | 10 | Inverse variance weighted | 0.217 | 1.926 (1.259, 2.946) | 0.003 |
| MR Egger | 0.507 | 0.975 (0.361, 2.631) | 0.961 | |||
| Simple mode | 0.536 | 1.540 (0.538, 4.404) | 0.441 | |||
| Weighted median | 0.311 | 1.492 (0.811, 2.745) | 0.198 | |||
| Weighted mode | 0.351 | 1.252 (0.630, 2.490) | 0.537 | |||
| Genus | Ruminococcus gnavus group | 12 | Inverse variance weighted | 0.139 | 0.731 (0.557, 0.960) | 0.024 |
| MR Egger | 0.656 | 0.538 (0.149, 1.943) | 0.366 | |||
| Simple mode | 0.269 | 0.608 (0.359, 1.030) | 0.091 | |||
| Weighted median | 0.187 | 0.648 (0.449, 0.933) | 0.020 | |||
| Weighted mode | 0.268 | 0.616 (0.365, 1.043) | 0.099 | |||
| Class | Candidatus Soleaferrea | 10 | Inverse variance weighted | 0.151 | 1.381 (1.027, 1.857) | 0.033 |
| MR Egger | 1.621 | 1.344 (0.056, 32.211) | 0.860 | |||
| Simple mode | 0.343 | 1.132 (0.577, 2.219) | 0.726 | |||
| Weighted median | 0.201 | 1.240 (0.835, 1.840) | 0.286 | |||
| Weighted mode | 0.323 | 1.114 (0.592, 2.096) | 0.747 | |||
| Holdemania | 14 | Inverse variance weighted | 0.154 | 0.737 (0.545, 0.997) | 0.048 | |
| MR Egger | 0.453 | 0.401 (0.165, 0.973) | 0.066 | |||
| Simple mode | 0.315 | 0.764 (0.412, 1.415) | 0.407 | |||
| Weighted median | 0.202 | 0.749 (0.504, 1.113) | 0.153 | |||
| Weighted mode | 0.319 | 0.738 (0.394, 1.380) | 0.358 |