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. 2024 Jul 22;21(10):1945–1963. doi: 10.7150/ijms.94335

Table 3.

MR result of casual effects between gut microbiome and the risk of delirium.

Group Bacterial Nsnp Methods SE OR (95% CI) P-value
Phylum Verrucomicrobia 12 Inverse variance weighted 0.183 1.444 (1.009, 2.065) 0.044
MR Egger 0.478 1.740 (0.682, 4.438) 0.273
Simple mode 0.411 2.053 (0.917, 4.596) 0.108
Weighted median 0.259 1.505 (0.906, 2.500) 0.114
Weighted mode 0.347 1.473 (0.746, 2.906) 0.288
Family Desulfovibrionaceae 10 Inverse variance weighted 0.217 1.926 (1.259, 2.946) 0.003
MR Egger 0.507 0.975 (0.361, 2.631) 0.961
Simple mode 0.536 1.540 (0.538, 4.404) 0.441
Weighted median 0.311 1.492 (0.811, 2.745) 0.198
Weighted mode 0.351 1.252 (0.630, 2.490) 0.537
Genus Ruminococcus gnavus group 12 Inverse variance weighted 0.139 0.731 (0.557, 0.960) 0.024
MR Egger 0.656 0.538 (0.149, 1.943) 0.366
Simple mode 0.269 0.608 (0.359, 1.030) 0.091
Weighted median 0.187 0.648 (0.449, 0.933) 0.020
Weighted mode 0.268 0.616 (0.365, 1.043) 0.099
Class Candidatus Soleaferrea 10 Inverse variance weighted 0.151 1.381 (1.027, 1.857) 0.033
MR Egger 1.621 1.344 (0.056, 32.211) 0.860
Simple mode 0.343 1.132 (0.577, 2.219) 0.726
Weighted median 0.201 1.240 (0.835, 1.840) 0.286
Weighted mode 0.323 1.114 (0.592, 2.096) 0.747
Holdemania 14 Inverse variance weighted 0.154 0.737 (0.545, 0.997) 0.048
MR Egger 0.453 0.401 (0.165, 0.973) 0.066
Simple mode 0.315 0.764 (0.412, 1.415) 0.407
Weighted median 0.202 0.749 (0.504, 1.113) 0.153
Weighted mode 0.319 0.738 (0.394, 1.380) 0.358