Fig 1.

Kinetics of fungal load in mouse skin tissue treated with and without cyclophosphamide. Mice were intradermally infected with C. auris AR0387. The control group received only fungal inoculation and CTX group received fungal inoculation and cyclophosphamide treatment. Each group consisting of 10 mice per group were euthanized on 1, 3, 7, 15 and 30 days post-infection and skin tissue were collected. Tissues were homogenized and plated onto YPD agar containing antibiotics. Data are represented as mean ±  SEM for each group. Statistical significance was calculated using unpaired student’s t-test for days 1,3, and 7; Mann-Whitney U-test was used for days 15 and 30. *P ≤ 0.05, **P ≤ 0.01, and ***P ≤ 0.001 were considered as significant.