Table 3.
Subgroup | HR (95%CI) | p value | p for interaction |
---|---|---|---|
Age | 0.371 | ||
< 65 (n = 1086) | 1.33 (1.24,1.43) | < 0.001 | |
≥ 65 (n = 1127) | 1.48 (1.38,1.59) | < 0.001 | |
Gender | 0.354 | ||
Female (n = 991) | 1.37 (1.28,1.47) | < 0.001 | |
Male (n = 1222) | 1.34 (1.24,1.44) | < 0.001 | |
SOFA | 0.485 | ||
< 6 (n = 755) | 1.27 (1.18,1.36) | < 0.001 | |
≥ 6 (n = 1458) | 1.29 (1.17,1.42) | < 0.001 | |
Hypertension | 0.542 | ||
NO (n = 1227) | 1.56(1.35,1.81) | < 0.001 | |
YES (n = 986) | 1.27(1.20,1.35) | < 0.001 | |
Cerebrovascular Disease | 0.086 | ||
NO (n = 1966) | 1.35 (1.28,1.42) | < 0.001 | |
YES (n = 247) | 1.57 (1.12,2.11) | 0.003 | |
Myocardial Infarction | 0.076 | ||
NO (n = 1916) | 1.35 (1.28,1.42) | < 0.001 | |
YES (n = 297) | 1.79 (1.34,2.41) | < 0.001 | |
Heart Failure | 0.354 | ||
NO (n = 1659) | 1.36 (1.29,1.44) | < 0.001 | |
YES (n = 554) | 1.33 (1.12,1.47) | < 0.001 | |
COPD | 0.003 | ||
NO (n = 1695) | 1.33 (1.25,1.40) | < 0.001 | |
YES (n = 518) | 2.12 (1.72,2.61) | < 0.001 | |
Ventilator | 0.548 | ||
NO (n = 307) | 1.39 (1.13,1.70) | 0.002 | |
YES (n = 1906) | 1.34 (1.27,1.41) | < 0.001 |
SOFA Sequential Organ Failure Assessment, COPD Chronic Obstructive Pulmonary Disease