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. 2024 Aug 6;25:624. doi: 10.1186/s12891-024-07702-9

Table 6.

ROC curve analysis for miRNA-26a, and miRNA-223 levels to discriminate disease activity and treatment non-response

Cut off value Sensitivity Specificity AUC
Disease activitya
miRNA-26a  ≥ 0.008 86.96 58.82 0.688
miRNA-223  ≥ 0.68 52.94 30.43 0.51
No treatment response by ACR 70 criteria
miRNA-26a  ≥ 0.008 85.7 52.63 0.67
miRNA-223  ≥ 0.85 66.67 68.42 0.6

ACR American College of Rheumatology

aDisease activity based on sJADAS-10 > 21