Fig 4. Plasma proteins associated with fibroproliferation on CT scan.

a) Increased levels of amphiregulin are associated with fibroproliferation on CT scan. Plasma protein levels were log₂-transformed and adjusted for age, sex, treatment with steroids, and enrollment APACHE III score. Plasma was collected 96-168h after enrollment. p-values reflect association of adjusted protein concentration with fibroproliferation using logistic regression. B) An increase in MMP-7 concentration over time (between plasma collected at 24h and at 96-128h) is associated with fibroproliferation. Plasma protein level was log₂-transformed. p-value reflects association of transformed protein concentration adjusted for age, sex, treatment with steroids, and enrollment APACHE III score with fibroproliferation seen on CT scan.