Table 4. Correlation of T790M mutation with clinicopathologic parameters at resection in EGFR-mutated cases (n=36).

Parameters	OR (95% CI)	P value
Tumor burden change at resection: regrowth vs. all others	1.615 (0.376–6.940)	0.52
EGFR mutation subtype	0.525 (0.119–2.312)	0.39
Lobectomy vs. sub-lobectomy	4.875 (0.872–27.262)	0.07
Lymph node dissection during resection	0.314 (0.069–1.433)	0.14
Objective of resection (curative vs. biopsy only)	3.152 (0.668–14.862)	0.15
Tumor differentiation level of resected sample (poorly differentiated vs. others)	0.686 (0.155–3.036)	0.62
Presence of STAS	10.5 (1.496–73.673)	0.02
Pleural invasion (yes or no)	0.132 (0.013–1.308)	0.08
Primary tumor size at resection (≥3 cm)	0.118 (0.013–1.074)	0.058
Resected sample PD-L1 ≥1% (SP263)	0.444 (0.060–3.285)	0.43
Resected sample PD-L1 ≥1% (22C3)	0.656 (0.108–4.003)	0.65
Prior EGFR TKI >12 months	9.231 (1.023–83.331)	0.048
Gender	1.037 (0.212–5.077)	0.96

EGFR, epidermal growth factor receptor; OR, odds ratio; CI, confidence interval; STAS, spread through air spaces; PD-L1, programmed death-ligand 1; TKI, tyrosine kinase inhibitor.