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. 2024 May 31;11(29):2400533. doi: 10.1002/advs.202400533

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© 2024 The Author(s). Advanced Science published by Wiley‐VCH GmbH

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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A) Expression of CD326 in serum of patients with ST‐segment elevation myocardial infarction (STEMI; red, n = 8), stable angina (SA; orange, n = 8). t Test CD326: p = 0.015. The study was conducted with MSP‐modified beads in a customized SiMoA assay as described in the Experimental Section. B) ROC curve analysis for individual EV markers: CD9/CD81/CD63 tetraspanins (blue curve), CD42a (green curve), CD62P (orange curve), CD326 (grey curve), and hs Troponin (red curve). C) Diagnostic performance of combined EV markers (black curve) in comparison with the gold standard hs troponin (red curve).