Table 1.

Rai and Binet system for CLL classification

Rai stage		Binet stage
0-	Lymphocytosis only	A	<3 Lymphadenopathies plus Lymphocytosis
I-	Stage 0 plus Lymphadenopathy	B	≥3 Lymphadenopathies plus Lymphocytosis
II-	Stage 0 plus Splenomegaly or hepatomegaly
III-	Stage 0 plus Anemia (hemoglobin <11 g/dL)	C	As for stage A or B Hemoglobin<10g/dL and/or platelet count <100 × 109/L
IV-	Stage 0 plus Thrombocytopenia (platelet count <100 × 109/L)