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TABLE 1.

Isolates used in molecular analysis of EV71a

Strainb Yr of isolation Origin Outcomec GenBank accession no.
BrCr-CA-70 1970 California Encephalitis U22521
2228-NY-72 1972 New York NA AF135867
2604-AUS-74 1974 Australia Meningitis AF135883
2605-AUS-74 1974 Australia Meningitis AF135884
2608-AUS-74 1974 Australia Meningitis AF135885
2609-AUS-74 1974 Australia Meningitis AF135886
2610-AUS-74 1974 Australia NA AF135887
2229-NY-76 1976 New York NA AF135868
2230-NY-76 1976 New York NA AF135869
2231-NY-77 1977 New York NA AF135870
2232-NY-77 1977 New York NA AF135871
2234-NY-77 1977 New York NA AF135872
2235-NY-77 1977 New York NA AF135873
2236-NY-77 1977 New York NA AF135874
2237-NY-77 1977 New York NA AF135875
2238-NY-77 1977 New York NA AF135876
2239-NY-77 1977 New York NA AF135877
10181-NM-78 1978 New Mexico NA AF138675
1011-ND-79 1979 North Dakota NA AF135864
2241-NY-79 1979 New York NA AF135878
2243-NY-79 1979 New York NA AF135879
2258-CA-79 1979 California Tremors AF135880
2114-TN-80 1980 Tennessee NA AF135866
2952-SD-81 1981 South Dakota NA AF135888
3663-MA-82 1982 Massachusetts NA AF135889
3885-UT-82 1982 Utah NA AF135891
3874-ND-82 1982 North Dakota NA AF135890
3982-OH-82 1982 Ohio Rash AF135892
3984-OH-82 1982 Ohio NA AF009538
2259-CA-82 1982 California Diarrhea AF135881
4224-MA-82 1982 Massachusetts Encephalitis AF135893
4323-UT-83 1983 Utah NA AF135894
4599-OR-83 1983 Oregon CNS disorder AF135895
4644-AR-83 1983 Arkansas NA AF135896
4826-CT-83 1983 Connecticut NA AF135897
4827-CT-83 1983 Connecticut NA AF009529
5115-TX-83 1983 Texas NA AF135898
0667-CHN-85 1985 Republic of China HFMD AF135934
2260-CA-86 1986 California Fever AF135882
2623-AUS-86 1986 Australia HFMD AF135945
6762-OK-86 1986 Oklahoma NA AF135900
1410-CA-86 1986 California Paralysis AF009525
0915-MA-87 1987 California Meningitis AF009549
0916-MA-87 1987 Massachusetts NA AF009550
1061-TN-87 1987 Tennessee NA AF009528
1413-CA-87 1987 California Paralysis AF009527
2219-IA-87 1987 Iowa Meningitis AF009539
2246-NY-87 1987 New York Paralysis AF009542
6910-OK-87 1987 Oklahoma Rash AF135901
7234-AK-87 1987 Alaska Paralysis AF009522
7235-AK-87 1987 Alaska Respiratory failure AF135902
7237-AK-87 1987 Alaska Diarrhea AF135951
7238-AK-87 1987 Alaska Rash AF135952
7289-NC-87 1987 North Carolina NA AF135903
7298-AK-87 1987 Alaska Fatality AF135904
7423-MS-87 1987 Mississippi Paralysis U22522
7628-PA-87 1987 Pennsylvania Paralysis AF009530
7629-PA-87 1987 Pennsylvania Gastroenteritis AF009531
7630-PA-87 1987 Pennsylvania Gastroenteritis AF009532
7631-PA-87 1987 Pennsylvania Gastroenteritis AF009533
7632-PA-87 1987 Pennsylvania Gastroenteritis AF135905
7633-PA-87 1987 Pennsylvania Gastroenteritis AF009534
7635-WA-87 1987 Washington Meningitis AF135906
7673-CT-87 1987 Connecticut NA AF009535
7962-PA-87 1987 Pennsylvania Paralysis AF009523
7968-PA-87 1987 Pennsylvania NA AF009524
8102-WA-87 1987 Washington Meningitis AF009526
8209-MD-87 1987 Maryland NA AF009536
8279-PA-87 1987 Pennsylvania NA AF009537
2222-IA-88 1988 Iowa Fever AF009540
8149-AL-88 1988 Alabama NA AF135907
8495-VA-88 1988 Virginia NA AF135953
9166-TX-89 1989 Texas NA AF135954
9243-OK-89 1989 Oklahoma NA AF135955
9323-TX-89 1989 Texas NA AF135956
9541-TX-89 1989 Texas NA AF009557
9718-TX-89 1989 Texas NA AF135957
9837-WA-89 1989 Washington NA AF135958
9873-NM-89 1989 New Mexico NA AF135959
9978-TX-89 1989 Texas Rash AF009558
0359-TX-90 1990 Texas NA AF135931
0390-TX-90 1990 Texas Otitis media AF135932
1411-CA-90 1990 California NA AF009551
0443-TX-90 1990 Texas NA AF135933
0925-OR-91 1991 Oregon Tremors AF009547
0926-OR-91 1991 Oregon NA AF009548
2261-CA-91 1991 California Meningitis AF135938
2583-CAN-91 1991 Quebec, Canada NA AF135944
2262-CA-92 1992 California Meningitis AF135939
2251-NY-93 1993 New York NA AF009543
1873-CT-94 1994 Connecticut Fatality AF009559
1919-NM-94 1994 New Mexico Rash AF009552
1924-AZ-94 1994 Arizona NA AF009553
1997-NC-94 1994 North Carolina NA AF135936
2006-CT-94 1994 Connecticut Rash AF009554
2007-CT-94 1994 Connecticut NA AF009555
2253-NY-94 1994 New York NA AF009544
2254-NY-94 1994 New York NA AF009545
2263-CA-94 1994 California Paralysis AF135940
2264-CA-94 1994 California Meningitis AF009546
6658-COL-94 1994 Colombia Paralysis AF135899
2037-MD-95 1995 Maryland NA AF009556
2132-VA-95 1995 Virginia NA AF135937
2640-AUS-95 1995 Australia NA AF135946
2641-AUS-95 1995 Australia HFMD AF135947
2642-AUS-95 1995 Australia Encephalitis AF135948
2644-AUS-95 1995 Australia NA AF135949
0731-MAA-97 1997 Malaysia (Sarawak) Fatality AF135911
0756-MAA-97 1997 Peninsular Malaysia NA AF135935
2286-TX-97 1997 Texas NA AF135941
2355-OK-97 1997 Oklahoma NA AF135942
2381-MA-97 1997 Massachusetts Fatality AF135943
2814-MO-98 1998 Missouri Meningitis AF135950
a

The sequences of BrCr-CA-70 and 7423-MS-87 were published previously (3). The sequence of CA16-G10-51 (24) (not shown) was included as an outgroup. 

b

The last four or five characters of each strain name indicate the state or country where isolated and the year of isolation. 

c

NA, not available. CNS, central nervous system.