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Probability of target attainment (PTA) for 5,000 patients receiving either standard (3 mg/kg q24h i.v.) or higher (5 mg/kg q24h i.v.) L-AMB dose were simulated with Monte Carlo analysis for different EUCAST and CLSI AMB MICs. Horizontal line corresponds to 95% PTAs. The epidemiological cut-off values for EUCAST (ECOFF) and CLSI (ECV) are shown for each species.
