TABLE 2.
Cumulative incidence of outcomesa
| Outcome, n (%) | 11–15-day therapy (N = 1161) |
5–10-day therapy (N = 246) |
Test of difference | Test of non-inferiority | Entirely intravenous (N = 349) |
Oral switch (N = 1112) |
Test of difference | Test of non-inferiority |
|---|---|---|---|---|---|---|---|---|
| Clostridioides difficile infection | 13 (1.1) | 0 (0.0) | <0.001 | <0.001 | 4 (1.1) | 11 (1.0) | <0.001 | <0.001 |
| Readmission | 221 (19.0) | 49 (19.9) | 0.75 | 0.080 | 75 (21.5) | 248 (22.3) | 0.75 | 0.04 |
| Recurrent streptococcal bacteremia | 14 (1.2) | 2 (0.8) | <0.001 | <0.001 | 2 (0.6) | 14 (1.3) | <0.001 | <0.001 |
| Death | 52 (4.5) | 6 (2.4) | 0.14 | <0.001 | 9 (2.6) | 59 (5.3) | 0.03 | 0.01 |
| Composite outcome | 241 (20.8) | 51 (20.7) | 0.99 | 0.047 | 80 (22.9) | 266 (23.9) | 0.70 | 0.06 |
a
Cumulative incidence expressed as N (%) for each treatment group.