Table 1.
Clinical characteristics of the study cohort (n = 156)
| Healthy Controls (n = 46) | SZ (n = 110) | P value | |
|---|---|---|---|
| SZ duration of illness, years | - | 15.7 (8.6–24.6) | - |
| Clozapine therapy, % | - | 91/110 (83) | - |
| Age, years | 37.5 (30.8–49.0) | 41.5 (31.0–52.3) | ns |
| Biological sex, M/F; %M | 22/24 (48) | 76/34 (69) | 0.01 |
| BMI, kg/m2 | 24.3 (22.9–26.5) | 28.5 (25.1–32.8) | <0.001 |
| HbA1c, % | 5.4 (5.2–5.5) | 5.7 (5.4–6.1) | 0.03 |
| Diabetes, % | 1/46 (2) | 23/110 (21) | 0.003 |
| Smoking, % current | 0/46 (0) | 44/110 (40) | <0.001 |
| Statin therapy, % | 0/46 (0) | 21/110 (19) | <0.001 |
Results are expressed as number and (%), or median and (interquartile range). HbA1c levels were determined in 14 controls and 106 patients.
BMI, body mass index; HbA1c, glycated hemoglobin; ns, non-significant; SZ, schizophrenia.