Table 1.
Patients’ Baseline Demographic and Anatomical Characteristics
| Total Cohort (N = 206) | Mitral Stenosis (n = 105) | Mitral Regurgitation (n = 75) | Mixed Disease (n = 26) | |
|---|---|---|---|---|
| Demographics | ||||
| Age, mo | 17.3 (4.6-56) | 11.9 (5.3-43.7) | 47.7 (5.3-72.9) | 4.6 (1.4-21.2) |
| Weight, kg | 9.1 (5-16.7) | 8.4 (5.4-13.2) | 13.7 (5.2-19.6) | 5.1 (3.3-11.4) |
| Follow-up, mo | 59.4 (18.3-108.4) | 63 (15.3-115.7) | 55.2 (16.8-87.4) | 76.8 (27.4-108.4) |
| Anatomical characteristics | ||||
| Double orifice mitral valve | 13 (6.3%) | 8 (7.6%) | 3 (4%) | 2 (7.7%) |
| Annular dilatation | 50 (24.3%) | 4 (3.8%) | 39 (52%) | 7 (26.9%) |
| Cleft leaflet | 46 (22.3%) | 0 (0%) | 39 (52%) | 7 (26.9%) |
| Elongated chordae | 10 (4.9%) | 0 (0%) | 10 (13.3%) | 0 (0%) |
| Shortened chordae | 76 (36.9%) | 47 (44.8%) | 17 (22.7%) | 12 (46.2%) |
| Absent chordae | 14 (6.8%) | 6 (5.7%) | 4 (5.3%) | 4 (15.4%) |
| Fused/closely spaced chordae | 45 (21.8%) | 37 (35.2%) | 3 (4%) | 5 (19.2%) |
| Secondary/abnormal chordae | 84 (41.0%) | 39 (37.1%) | 26 (34.7%) | 17 (65.4%) |
| Commissural fusion | 30 (14.6%) | 26 (24.8%) | 0 (0%) | 4 (15.4%) |
| Hammock valve (mitral arcade) | 22 (10.7%) | 12 (11.4%) | 3 (4%) | 7 (26.9%) |
| Stenosing mitral membrane | 65 (31.6%) | 62 (59.0%) | 0 (0%) | 3 (11.5%) |
| Endocardial fibroelastosis | 62 (30.1%) | 46 (43.8%) | 8 (10.7%) | 8 (30.8%) |
| Single dominant papillary muscle | 27 (13.1%) | 22 (21.0%) | 4 (4%) | 1 (3.8%) |
| Prolapse of the anterior leaflet | 51 (24.8%) | 5 (4.8%) | 35 (46.7%) | 11 (42.3%) |
| Thickened leaflets | 110 (53.4%) | 64 (61.0%) | 30 (40.0%) | 16 (61.5%) |
| Tethered leaflets | 115 (55.8%) | 58 (55.2%) | 34 (45.3%) | 23 (88.5%) |
| Tethered papillary muscles | 94 (45.6%) | 51 (48.6%) | 23 (30.7%) | 20 (76.9%) |
| Closely spaced papillary muscles | 34 (16.5%) | 28 (26.7%) | 0 (0%) | 6 (23.1%) |
Values are median (IQR) or n (%).