FIG. 1.

Schematic representation of the expression plasmids used in this study. The organization of the nonstructural region of the viral polyprotein is shown at the top. Each numbers above the bar indicates the position of the N-terminal amino acid of the following protein within the viral polyprotein. The horizontal line indicates the 3′ UTR. R, ribozyme sequence. The vertical bars indicate the boundaries between the different proteins. The HCV polyprotein portions expressed by the different constructs are shown below. myc, epitope with the amino acid sequence EQKLISEEDL; A, the mutation S1165A in NS3.