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Pyrotinib-related adverse events.
| Any events, No (%) | Grade 3, No (%) | |
|---|---|---|
| Diarrhea | 128 (93.43) | 26 (18.98) |
| Hand-foot syndrome | 63 (45.99) | 5 (3.65) |
| Nausea | 56 (40.88) | 0 (0) |
| Asthenia | 42 (30.66) | 0 (0) |
| Leukopenia | 39 (28.47) | 3 (2.19) |
| Vomiting | 30 (21.90) | 0 (0) |
| ALT/AST increased | 26 (18.98) | 2 (1.46) |
| Thrombocytopenia | 25 (18.25) | 0 (0) |
| Stomatitis | 13 (9.49) | 0 (0) |
| Rash | 9 (6.57) | 0 (0) |
