Table 1. BTIC cell line patient characteristics.
BTIC line | Patient age at surgery | Biological sex | Molecular subtype | Methylation subtype | CNV gains | CNV losses | MGMT methylated | Reference |
---|---|---|---|---|---|---|---|---|
GBM1A | – | M | Classical/Proneural | Indeterminate | MDM4, MYCN, TERT, EGFR, CDK6, MET, KIAA1549/BRAF | RB1, TP53 | Y | (32, 94) |
QNS120 | 59 | M | Classical | RTKII | FGFR3/TACC3, PDGFRA, TERT, MET, MYBL1, CCND2 | MDMA, MYB, CDKN2A/B, PTCH1, PTEN, MGMT, CCND1, NF1, C19MC | Y | (93) |
GBM965 | 61 | F | Classical | RTKII | EGFR, CDK6, MET, KIAA1549/BRAF | CDKN2A/B, NF1 | Y | (32, 114) |