Table 2.

Covariate analysis

	Antibody binding IgG IgM, IgA Spike 1 WT	Antibody binding IgG IgM, IgA RBD WT	Antibody binding IgG only RBD WT	Pseudovirus neutralization WT	Pseudovirus neutralization WT Asthmatics in each group only	Live Virus Neutralization D614G
PoB vs. NB	−34,778 (0.01)	−33,776 (0.02)	−36,253 (0.009)	−0.27 (0.05)	−0.95 (<.0001)	−130.66 (0.008)
Age	−28.12 (0.94)	−191.85 (0.60)	23.85 (0.95)	−0.004 (0.25)	−0.006 (0.14)	−0.74 (0.56)
Race
Black	−17,474 (0.28)	−18,762 (0.26)	−8,153.52 (0.62)	−0.25 (0.07)	0.03 (0.82)	−6.77 (0.86)
Asian	−32,959 (0.09)	−31,658 (0.11)	−17,623 (0.36)	−0.26 (0.25)	−0.12 (0.62)	46.41 (0.39)
White (ref)	0.0	0.0	0.0	0.0	0.0	0.0
Female vs male	−4,144.48 (0.70)	6,249.52 (0.58)	−4,282.71 (0.70)	0.05 (0.61)	0.16 (0.19)	−9.97 (0.76)
Asthma yes vs no	−2,582.92 (0.85)	1,627.50 (0.91)	2,715.83 (0.84)	−0.09 (0.48)		97.93 (0.03)

Table 2 Legend: After adjusting for differences in the baseline characteristics of age, race, gender, and asthma status we found that PoB had significantly lower values in the outcome variables of antibody binding and pseudovirus neutralization than NB (p =< 0.05, bold). The adjusted covariates of age, race, gender, and asthma status were not significant in predicting the outcomes (P > 0.05) in all except for the live virus neutralization where subjects with asthma actually had a significantly higher neutralization than subjects without asthma. The top number in each box represents the difference in means between the groups compared. For age that is a continuous variable, it represents the change in the outcome variable for every 1-year increase of age. The bottom number in parenthesis represents the p-value of each comparison. All comparisons in this table were done at the 6-month timepoint after the second vaccination dose.