Table 3. MRI protocol for ARIA.

Component	MRI protocol
Scanner field strength	1.5T (minimum) or 3T (recommended)
Slice thickness	≤5 mm
Echo time	≥20 ms
Scan time	≤15 min (recommended)
Imaging sequence	T2-FLAIR (2D or 3D): For ARIA-E (vasogenic edema in the parenchyma, effusion and exudate in the leptomeninges)
	T2* GRE (or SWI)*: For ARIA-H (microhemorrhage in the parenchyma, superficial siderosis in the leptomeninges)
	Diffusion-weighted imaging: For the differential diagnosis of cytotoxic edema including acute infarction
	3D T1-imaging (optional): For the assessment of brain atrophy and disease progression

^*The sequence of the baseline and follow up monitoring MRI (T2* GRE or SWI) should be consistent and matching.

ARIA = amyloid-related imaging abnormalities, D = dimensional, GRE = gradient echo, SWI = susceptibility-weighted imaging