Table 4. Univariable and multivariable Cox proportional hazard regression analysis analyses for time to local tumor progression.
| Variable | Univariable | Multivariable | |||
|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P | Hazard ratio (95% CI) | P | ||
| Age (for increase by 1 year) | 1.004 (0.985, 1.023) | 0.709 | |||
| Sex | |||||
| Male | Reference | ||||
| Female | 0.924 (0.606, 1.408) | 0.712 | |||
| Portal hypertension | |||||
| No | Reference | ||||
| Yes | 0.826 (0.546, 1.250) | 0.366 | |||
| Tumor size, cm | |||||
| ≤3 | Reference | Reference | |||
| >3 | 1.303 (0.862, 1.969) | 0.210 | 1.310 (0.855, 2.009) | 0.215 | |
| Child-Pugh classification | |||||
| A | Reference | ||||
| B | 0.854 (0.465, 1.569) | 0.612 | |||
| Increased tumor marker | |||||
| No | Reference | Reference | |||
| Yes | 1.612 (1.056, 2.459) | 0.027 | 1.614 (1.058, 2.464) | 0.026 | |
| Bead size, μm | |||||
| 70–150 | Reference | Reference | |||
| 100–300 | 1.257 (0.831, 1.902) | 0.279 | 1.331 (0.868, 2.042) | 0.190 | |
Variable selection in the multivariable model was performed using backward elimination of all variables included in this study.
CI = confidence interval