FIGURE 9.
The effect of LM11A-31 on inflammatory response in U1 macrophages. U1 macrophages were differentiated and then treated with DMSO, LM11A-31 (100 nM), DRV (5.5 μM), and LM11A-31 + DRV for 48 h. The cytokines and chemokines profile were measured using a customized human 9-Plex ProcartaPlex™ multiplex immunoassay. (A) Proinflammatory, chemokines, and anti-inflammatory measurement at 24 h. (B) Proinflammatory, chemokines, and anti-inflammatory measurement at 48 h. Values are expressed as mean SEM (n = 4–6). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001.(b)